The steroid hormone aldosterone is a potent mineral corticoid that is produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. The synthesis and release are controlled by the renin- angiotensin - aldosterone sy stem (RAAS), as well as by plasma potassium concentration, the pituitary peptide ACTH, and by the blood pressure via pressure sensitive baroreceptors in the vessel walls of nearly all large arteries of the body. Aldosterone binds to mineralocorticoid receptors (MR) and triggers the transcription of hormone - responsive genes. In consequence, aldosterone increases the blood pressure by reabsorption of sodium and water from the distal tubules of the kidney into the blood, secretion of potassium into the urine, and elevation of circulating blood volume. Chronic overproduction and secretion of aldosterone leads to hypertension. Aldosterone activity is reduced in Addison's disease and increased in Conn's syndrome. Measurement of aldosterone levels in serum in conjunction with plasma renin levels can be used to differentiate between primary and secondary aldosteronism.
SI units Conversion Calculator. Convert Aldosterone level to nmol/L, ng/mL, ng/dL, ng/100mL, ng%, ng/L, pg/mL. Clinical laboratory units online conversion from conventional or traditional units to Si units. Table of conversion factors for Aldosterone unit conversion to nmol/L, ng/mL, ng/dL, ng/100mL, ng%, ng/L, pg/mL.