Lactate (Lactic Acid)
Anaerobic glycolysis markedly increases blood lactate and causes some increase in pyruvate levels, especially with prolonged exercise. The common cause for increased blood lactate and pyruvate is anoxia resulting from such conditions as shock, pneumonia and congestive heart failure. Lactic acidosis may also occur in renal failure and leukemia. Thiamine deficiency and diabetic ketoacidosis are associated with increased levels of lactate and pyruvate.
Lactate levels in cerebrospinal fluid (CSF) are increased in bacterial meningitis. Increased CSF levels also occur in hypocapnia, hydrocephalus, brain abscesses, cerebral ischemia and any clinical condition associated with reduced oxygenation of the brain and/or increased intracranial pressure. Lactate measurements that evaluate the acid‐base status are used in the diagnosis and treatment of lactic acidosis (abnormally high acidity in the blood).
SI units Conversion Calculator. Convert Lactate (Lactic Acid) level to mmol/L, µmol/L, mg/dL, mg/100mL, mg%, mg/L, µg/mL. Clinical laboratory units online conversion from conventional or traditional units to Si units. Table of conversion factors for Lactate (Lactic Acid) unit conversion to mmol/L, µmol/L, mg/dL, mg/100mL, mg%, mg/L, µg/mL.