Insulin- like growth factor binding protein 3 (IGFBP-3)

SI UNITS (recommended)

CONVENTIONAL UNITS



* The SI unit is the recommended method of reporting clinical laboratory results

Units of measurement
µg/mL, µg/dL, µg/100mL, µg%, µg/L , mg/L

Insulin-like growth factors (IGF-I, IGF-II) are a family of peptides involved in the regulation of cell growth, the actions of which are mediated by binding to the insulin-like growth factor binding proteins. Six binding proteins (IGFBP-1 through IGFBP-6) have been described. IGFBP-3 is the most predominant of these. IGFBP-3 is a 264-amino acid peptide (MW 29kD) which forms a 150kD glycoprotein complex consisting of IGFBP-3 itself and an IGF molecule. Approximately 95% of IGF-I and IGF-II are bound to IGFBP-3, which makes this protein the major carrier of the insulin-like growth factors in circulation. The function of the binding protein is to extend the half-life of the growth factors in the circulation, to several hours.

IGFBP-3 is used as an aid in the evaluation of growth disorders. It is growth hormone (GH) dependent and therefore useful in the evaluation of GH secretion.

SI units Conversion Calculator. Convert Insulin- like growth factor binding protein 3 (IGFBP-3) level to µg/mL, µg/dL, µg/100mL, µg%, µg/L , mg/L . Clinical laboratory units online conversion from conventional or traditional units to Si units. Table of conversion factors for Insulin- like growth factor binding protein 3 (IGFBP-3) unit conversion to µg/mL, µg/dL, µg/100mL, µg%, µg/L , mg/L .