Vitamin B6 (Pyridoxal Phosphate)
Pyridoxine (vitamin B6) is a complex of six vitamers: pyridoxal, pyridoxol, pyridoxamine (pyridoxine), and their 5′-phosphate esters. Because of its role as a cofactor in a number of enzymatic reactions, pyridoxal phosphate (PLP) has been determined to be the biologically active form of vitamin B6. Vitamin B6 is important in heme synthesis and functions as a coenzyme in amino acid metabolism and glycogenolysis. Vitamin B6 deficiency is associated with symptoms of irritability, weakness, depression, dizziness, peripheral neuropathy, and seizures. In the pediatric population, deficiencies have been characterized by diarrhea, anemia, and seizures.
Vitamin B6 is ubiquitous. Vitamin B6 is three related compounds: pyridoxine, occurring mainly in plants; and pyridoxal and pyridoxamine, which are present in animal products. The major dietary sources of vitamin B6 are meat, poultry, fish, potatoes, and vegetables; dairy products and grains contribute lesser amounts. Readily absorbed from the intestinal tract, vitamin B6 is excreted in the urine in the form of metabolites. Vitamin B6 deficiency rarely occurs alone; it is more commonly seen in patients deficient in several B vitamins. Those particularly at risk for deficiency are patients with uremia, liver disease, absorption syndromes, malignancies, or chronic alcoholism. High intake of proteins increases the requirements for vitamin B6. Deficiency is associated with hyperhomocystinemia. Vitamin B6 has low toxicity because of its water-soluble nature; however, extremely high doses may cause peripheral neuropathy. The RDA of vitamin B6 is 1.3–1.7 mg/day for adult males and 1.3–1.5 mg/day for adult females, depending on age.
|Nanomole per liter||
nmol/L = nM/L = nanomol/L
|Microgram per liter||µg/L = mcg/L = ug/L= microg/L = microgram/L = µg/liter = mcg/liter = ug/liter|
|Microgram per deciliter||µg/dL = mcg/dL = ug/dL= microg/dL = microgram/dL|
|Microgram per 100 milliliters||µg/100mL = mcg/100mL = ug/100mL= microg/100mL = microgram/100mL|
|Microgram percent||µg% = mcg% = ug%= microg% = microgram%|
|Nanogram per milliliter||ng/mL = nanog/mL = nanogram/mL|
Lab units Conversion Calculator. Convert Vitamin B6 (Pyridoxal Phosphate) level to nmol/L, µg/L, µg/dL, µg/100mL, µg%, ng/mL
. Clinical laboratory units online conversion from conventional or traditional units to Si units. Table of conversion factors for Vitamin B6 (Pyridoxal Phosphate).